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One of the most pernicious consequences of COVID-19 on society is how it has affected global mental health, creating new problems and aggravating existing ones. Mental health issues and therapy typically take a backseat when the limited resources are equipped for the pandemic. So, it is necessary to track any psychological problems before they get out of our hands. This paper focuses on building a mental health tracker using a machine learning algorithm which mainly concentrates on cognitive mental disorder. It is critical in ensuring that these are caught early and one of the screening tools used for that is MMSE evaluation;it provides a quantitative assessment of cognitive impairment and to log cognitive changes over time. Using K-means clustering algorithm clusters are formed with the possibility of dementia occurrence. © 2022 IEEE.
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Covid-19 has shaken the entire globe. In the fight against this pandemic, the doctors and frontline workers are the real heroes who are facing an unseen enemy. The Masks, PPE Kits, and other protective wearables are used by patients, doctors, and other front-line workers for only one time. This leads to increased costs and supply issues, and also leads to huge environmental pollution. That is the problem that the product 'Safe Box' Addresses. The proposed system sterilizes Masks, PPE Kits, and other wearables making them reusable. 'Safe Box' plays a vital role in aiding hospitals, laboratories, clinics, and other healthcare facilities where non-reusable kits like masks, PPE, and other wearables are widely used. © 2022 IEEE.
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BACKGROUND: Medical students are likely to be exposed to COVID-19 patients, so achieving high vaccination coverage rates for COVID-19 in this group is mandatory.Willingness to vaccinate against SARS-CoV-2 as soon as possible depends on several factors.Based on this perspective, this study aims to determine vaccine acceptance among undergraduate medical students and study the barriers toCOVID-19 vaccination including various myths and misconceptions among the students. METHODOLOGY: The current cross-sectional study was carried out among 400 undergraduate medical students in a tertiary health centre in Chennai by using simple random sampling method. A semi-structured questionnaire was utilized to obtain information about the socio-demographic data, myths and concerns regarding COVID-19 vaccination. RESULTS:All the students are vaccinated against COVID-19. Above 50% of students are concerned about the serious adverse events from the currently available COVID-19 vaccines. Nearly 60% of students perceive themselvesas not at elevated risk of acquiringCOVID-19infection. Around 40% of students think all age groupsare eligible for COVID-19 vaccination. Only 5.8% of students believevaccine approval alone does not guarantee its safety. CONCLUSION:The undergraduate medical students lack awareness regarding COVID-19 vaccination eligibility, concerns regarding adverse events and the efficacy of the COVID-19 vaccine.As future health care providers, medical students' concerns should be prioritized.
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Introduction:In the context of the COVID-19 pandemic, studies on perinatal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection play an essential role in the understanding of the disease which in turn is necessary for optimal management of affected neonates.Aim and Objective:To determine the clinical outcomes in neonates born to mothers with SARS-CoV-2 infection and to identify possible risk factors in perinatal transmission.Materials and Methods:This was a retrospective cohort study performed at level-3 teaching Neonatal Intensive Care Unit (NICU) in South India. Medical records of all mothers who delivered in the COVID-19 facility and neonates born to COVID-19 confirmed mothers from April 15, 2020, to September 15, 2021, were collected and analyzed.Results:Of 15,720 deliveries, 556 mothers who tested positive for COVID-19 delivered 563 babies (7 twins), of which 6.3% were positive for SARS-CoV-2. Out of 563 babies, 14.5% were preterm and 95% were asymptomatic. Among COVID-19 positive mothers, cesarean was the most common mode of delivery (73.5% and 88% in COVID-19 positive and negative neonates respectively;P value = .01) and most of the babies were roomed-in (85.2% in COVID-19 positive and 94.6% in COVID-19 negative neonates;P value = .02). COVID-19 positive neonates had significantly high probability of pneumonia (P value = .003), sepsis (P value = .03), septic shock (P value = .01), and abnormal CXR (P value = .01). There was no significant difference in the mortality rate.Conclusion:COVID-19 positive status of the mother is not associated with increased risk of preterm birth, neonatal admission, morbidity, or mortality. The risk of transmission was not found to be associated with direct breastfeeding or rooming-in.
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Background: Patients with cancer are at higher risk of developing COVID-19 disease, adverse outcomes, and increased mortality. Phase III COVID-19 vaccine trials have demonstrated safety/efficacy against COVID-19 and prevented hospitalizations and deaths;however, most excluded ptcpts with cancer. We present phase 3 tozinameran mRNA COVID-19 vaccine trial results from ptcpts with a cancer history at baseline, either ongoing or not, per the Charlson Comorbidity Index and up to 6 months of follow-up. Methods: Between Jul 2020-Jan 2021, 46429 ptcpts ≥12 y at 152 sites in 6 countries were randomized in a placebo-controlled, observer-blinded trial of 2-dose tozinameran, showing 95% protection against COVID-19 and favorable safety (Polack et al NEJM, Dec 2020). After emergency use authorization, ptcpts were allowed to unblind and placebo recipients received vaccine. Data prior to unblinding for crossover up to 13 Mar 2021 are presented for ptcpts ≥16 y for safety and ≥12 y for efficacy. Adverse event (AE) data are controlled for follow-up time before unblinding and reported as incidence rate (IR) per 100-person-y of follow-up. Results: Of ptcpts ≥16 y, 1647 had a prior diagnosis of cancer and were not on active immunosuppressive treatment (755 M;892 F;median age 66 y [range 22-91]). Most common solid cancers included breast (n=458), prostate (n=360), and melanoma (n=210). AEs were reported at IRs of 94.0 (vaccine) and 49.3 (placebo) per 100-person-y;most common AEs were reactogenicity events (injection-site pain [IR: 40.2 vaccine;4.2 placebo];fatigue [IR: 21.4 vaccine;7.6 placebo];pyrexia [IR: 19.8 vaccine;0.7 placebo]). 1 vaccine ptcpt withdrew due to a vaccine-related AE. No vaccine-related deaths were reported. Among ptcpts ≥12 y with cancer, 3 vaccine and 27 placebo recipients developed COVID-19 from 7 days post-Dose 2;vaccine efficacy (VE) was 89.7% (95% CI 66.5-98.0%). This compares favorably with overall VE of 91.1%. Updated results will be presented. Conclusions: Tozinameran has similar efficacy/safety in ptcpts with cancer as in the overall population. These results inform tozinameran use in COVID-19 and in future trials in patients with cancer. Clinical trial identification: NCT04368728. Editorial acknowledgement: Editorial assistance was provided by Erin Bekes, PhD, of CMC AFFINITY, McCann Health Medical Communications, and was funded by Pfizer. Legal entity responsible for the study: Study sponsored by BioNTech, managed by Pfizer. Funding: Pfizer and BioNTech. Disclosure: S.J. Thomas: Financial Interests, Personal and Institutional, Research Grant, Advisory role: Pfizer. J.L. Perez: Financial Interests, Personal, Full or part-time Employment, Stocks/Shares: Pfizer. S.P. Lockhart: Financial Interests, Personal, Full or part-time Employment, Stocks/Shares: Pfizer. S. Hariharan: Financial Interests, Personal, Full or part-time Employment, Stocks/Shares: Pfizer. N. Kitchin: Financial Interests, Personal, Full or part-time Employment, Stocks/Shares: Pfizer. R. Bailey: Financial Interests, Personal, Full or part-time Employment, Stocks/Shares: Pfizer. K. Liau: Financial Interests, Personal, Full or part-time Employment, Stocks/Shares: Pfizer. E. Lagkadinou: Financial Interests, Personal, Full or part-time Employment: BioNTech. Ö. Türeci: Financial Interests, Personal, Research Grant: BioNTech. U. Şahin: Financial Interests, Personal, Research Grant: BioNTech. X. Xu: Financial Interests, Personal, Full or part-time Employment, Stocks/Shares: Pfizer. S.S. Dychter: Financial Interests, Personal, Full or part-time Employment, Stocks/Shares: Pfizer. C. Lu: Financial Interests, Personal, Full or part-time Employment: Pfizer. W. Gruber: Financial Interests, Personal, Full or part-time Employment, Stocks/Shares: Pfizer. All other authors have declared no conflicts of interest.
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Background: The COVID-19 pandemic has had an appreciable impact on public mental health. Hence continuous monitoring of the population's mental health especially during a pandemic demands immediate attention. The COVID-19 pandemic contributing to a rise in depression and anxiety among college students, with more than one third of them experiencing detrimental mental health challenges. Objective: The objective of this study was to investigate the prevalence of depression and anxiety during the COVID-19 pandemic among medical college students. Methods: This study was conducted among 500 medical college students, after getting approval from the Institutional Ethical Committee. Pre-structured questionnaire-based DASS21 scale was used for this study through Google form after obtaining written consent from the students. Using Google Form, a structured e-questionnaire was created and the link was shared via email. All the data were analysed using SPSS ver24. Results are given in frequency and percentage Results: In our study, we found that prevalence of depression and anxiety, among college students was 16%, and 18%, respectively. Conclusion: In our study, we found that anxiety, depression, and stress were present among medical students. In COVID-19 phase, students were not attending medical colleges and all the teaching process was online. Even at home, medical students were suffering from anxiety, depression, and stress. Early evaluation and intervention should be prioritized to reduce these morbidities among the medical students.,Depression, anxiety, college students.
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Objectives: The purpose of this study was to investigate students' thought processes during this extended COVID-19 lockdown and to ascertain their views about online education, their main current apprehensions and worries, their stress levels, and their view of an eventual post-COVID-19 return to college. Methods: An online survey was conducted on 300 plus students of the PSG College of Pharmacy, India. The survey was split gender-wise and across senior-junior years. Results: Three out of the four groups showed an overall desire to return to college and resume normal operations with reasonable social distancing norms. All the student groups surveyed were extremely keen on resuming practical labs but showed mixed feelings towards resuming traditional examination methods. All the groups showed stress and uncertainty regarding the lockdown. Conclusion: A reasonable picture could be obtained from student feedback and thoughts pertaining to during and after the COVID-19 lockdown. These preliminary findings may help educators formulate appropriate policies to address students' issues.